Table 6.
Relative risks (RR) and 95% confidence intervals (95% CI) for the presence of a risk factor for cardiovascular disease in the entire cohort
| |
Univariate |
Multivariate (n = 409) |
||||
|---|---|---|---|---|---|---|
| RR | 95% CI | P value | RR | 95% CI | P value | |
| Diabetes (present vs. absent) |
3.2 |
1.9-5.6 |
<0.001 |
3.6 |
2.0-6.5 |
<0.001 |
| Male sex |
2.9 |
2.0-4.3 |
<0.001 |
2.4 |
1.6-3.7 |
<0.001 |
| Lp (a) (high vs. low)* |
1.6 |
1.0-2.6 |
0.033 |
1.8 |
1.1-2.9 |
0.014 |
| HDL-C (mmol L-1) |
0.2 |
0.1-0.4 |
<0.001 |
0.4 |
0.2-0.7 |
0.004 |
| Family history pre-mature CVD |
1.5 |
1.1-2.3 |
0.026 |
1.8 |
1.2-2.7 |
0.005 |
| LDL-C (mmol L-1) |
0.8 |
0.6-0.9 |
0.002 |
0.8 |
0.7-0.9 |
0.001 |
| Smoking (ever vs. never) | 2.1 | 1.4-3.0 | <0.001 | - | - | - |
*:Lp (a) analysis carried out on the 276 FH patients with Lp (a) data available.