Table 1.
Correlation of perineural invasion with patients’ clinicopathological features in primary esophageal squamous cell carcinomas
| Variables |
Perineural invasion |
|||
|---|---|---|---|---|
| Cases | Absent | Present | P value* | |
| Age (years) |
|
|
|
0.083 |
| ≤ 57.0† |
230 |
110 (47.8%) |
120 (52.2%) |
|
| > 57.0 |
203 |
114 (56.2%) |
89 (43.8%) |
|
| Gender |
|
|
|
0.502 |
| Female |
112 |
61 (54.5%) |
51 (45.5%) |
|
| Male |
321 |
163 (50.8%) |
158 (49.2%) |
|
| Location |
|
|
|
0.098 |
| Upper |
28 |
14 (50.0%) |
14 (50.0%) |
|
| Middle |
298 |
145 (48.7%) |
153 (51.3%) |
|
| Lower |
107 |
65 (60.7%) |
42 (39.3%) |
|
| Tumor size (cm) |
|
|
|
0.952 |
| ≤ 4‡ |
277 |
143 (51.6%) |
134 (48.4%) |
|
| > 4 |
156 |
81 (51.9%) |
75 (48.1%) |
|
| Differentiation |
|
|
|
0.017 |
| Well |
67 |
41 (61.2%) |
26 (38.8%) |
|
| Moderate |
288 |
153 (53.1%) |
135 (46.9%) |
|
| Poor |
78 |
30 (38.5%) |
48 (61.5%) |
|
| pT status |
|
|
|
0.036 |
| T1 |
20 |
15 (75.0%) |
5 (25.0%) |
|
| T2 |
104 |
59 (56.7%) |
45 (43.3%) |
|
| T3 |
309 |
150 (48.5%) |
159 (51.5%) |
|
| pN status |
|
|
|
< 0.0001 |
| N0 |
233 |
137 (58.8%) |
96 (41.2%) |
|
| N1 |
111 |
59 (53.2%) |
52 (46.8%) |
|
| N2 |
71 |
25 (35.2%) |
46 (64.8%) |
|
| N3 |
18 |
3 (16.7%) |
15 (83.3%) |
|
| Stage |
|
|
|
< 0.0001 |
| I |
25 |
19 (76.0%) |
6 (24.0%) |
|
| II |
238 |
138 (58.0%) |
100 (42.0%) |
|
| III | 170 | 67 (39.4%) | 103 (60.6%) | |
*Chi-square test; †Median age; ‡Median size.