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The effect of symptomatic treatment with sumatriptan and P2X7-selective antagonist BBG. Wild-type mice were treated with 600 μg/kg sumatriptan/50 mg/kg BBG i.p. or an identical volume of saline 5 min after NTG treatment. PWT is expressed in % of baseline. Asterisk indicate significant changes between respective PWT values of saline- and sumatriptan-treated mice (n = 10 animals/group; ANOVA + Fischer LSD post hoc test, *P < 0.05).
