Table 5.
Summary of the ECM-Remodeling Protein Changes Between Secretory and Proliferative Phases for Patients With POP Versus Control Asymptomatic Women.
| ECM Remodeling Proteins | ADAMTS2 | MMP-2 | MMP-9 | MMP-12 | TIMP-1 | TIMP-2 | TIMP-3 | TIMP-4 |
|---|---|---|---|---|---|---|---|---|
| Proliferative (POP vs control) |
|
|
|
|
|
|
|
|
| Secretory (POP vs control) |
|
|
|
|
|
|
|
|
Abbreviations: ADAMTS, A Disintegrin And Metalloproteinase with Thrombospondin Motifs; ECM, extracellular matrix; MMP, matrix metalloproteinase; POP, pelvic organ prolapse; TIMP, tissue inhibitors of metalloproteinases.