Table 1.
Maternal and Sample Variables Examined in First-Trimester Serum.a
| Control (n = 37 Including 2 Preterm) | PE (n = 6 Including 1 Preterm) | PE/SGA (n = 1) | SGA (n = 17) | |
|---|---|---|---|---|
| Maternal age at draw date, years | 34.3 ± 0.6 | 36.7 ± 1.3 | 36.0 | 34.9 ± 0.6 |
| Maternal weight, kg | 64.4 ± 2.0 | 62.9 ± 2.7 | 61.0 | 59.9 ± 2.9 |
| Gestional age on draw date, weeks | 11.8 ± 0.1 | 12.4 ± 0.4 | 11.7 | 11.6 ± 0.2 |
| Freeze time, months | 42.4 ± 1.2 | 42.0 ± 4.3 | 46.0 | 41.2 ± 2.6 |
| % Parous | 54 | 33 | 100 | 24 |
| Ethnicity | ||||
| Caucasian/Asianb/East Asian | 31/1/5 | 3/1/2 | 1/0/0 | 9/0/8 |
| Birth weight, g | ||||
| Including preterm(s) | 3468 ± 81.7 | 3138 ± 321.0 | c | c |
| Excluding preterm(s) | 3551 ± 60.8 | 3426 ± 174.5 | 2180 | 2633 ± 31.1 |
| Gestional age at delivery, weeks | ||||
| Including preterm(s) | 39.1 ± 0.3 | 37.5 ± 0.8 | c | c |
| Excluding preterm(s) | 39.4 ± 0.2 | 38.2 ± 0.6 | 37.0 | 40.0 ± 0.2 |
| Mean PAPP-A2, ng/mL | ||||
| Including preterm(s) | 23.3 ± 2.0 | 35.2 ± 2.8 | c | c |
| Excluding preterm(s) | 22.2 ± 1.6 | 35.7 ± 3.4 | 19.8 | 23.7 ± 2.6 |
| MoM PAPP-A | 1.20 ± 0.1 | 1.17 ± 0.3 | 1.14 | 0.76 ± 0.1 |
Abbreviations: MoM, multiples of the median; PAPP-A, pregnancy-associated plasma protein A; PAPP-A2, pregnancy-associated plasma protein A2; PE, preeclampsia; SGA, small-for-gestational-age.
aValues represented as mean ± standard error of the mean.
bFor example, India, Pakistan, and Bangladesh.
cThe PE/SGA and SGA sample sets contained no preterms.