Figure 7.

X-ray images of sagittal (A,C,E,G,I,K) and horizontal (B,D,F,H,J,L) sections hybridized with an oligonucleotide probe specific for SK3 show the distribution of this channel subunit in the rat CNS at postnatal stages P1, P3, P6, P12, and P24. The hybridization pattern differs substantially from the patterns of SK1 (Fig. 5) and SK2 (Fig. 6) and shows strong SK3 mRNA expression in the accessory olfactory bulb, anterior olfactory nucleus (AO) and olfactory tubercle, hippocampus (Hi), basal ganglia, septum, amygdala, thalamus (Th), and several hypothalamic and brainstem nuclei. For details on the distribution see Table6. Control sections (K,L) hybridized in the presence of 100-fold excess cold oligonucleotide show a low and uniform background signal. For abbreviations see list. Scale bar = 4 mm.