Table 3.
Non-Hodgkin lymphoma and Kaposi sarcoma in AIDS-associated autopsies
| |
|
Total |
ART (−) patients |
ART (+) patients |
P values |
||||
|---|---|---|---|---|---|---|---|---|---|
| n | % | n | % | n | % | ||||
| All NHL cases |
|
71 |
100.0% |
41 |
100.0% |
25 |
100.0% |
|
|
| Histology |
DLBCL |
53 |
74.6% |
30 |
73.2% |
18 |
72.0% |
0.917 |
|
| |
BL |
4 |
5.6% |
3 |
7.3% |
1 |
4.0% |
0.987 |
Y |
| |
PEL |
5 |
7.0% |
4 |
9.8% |
1 |
4.0% |
0.706 |
Y |
| |
PBL |
1 |
1.4% |
1 |
2.4% |
0 |
0.0% |
0.801 |
Y |
| |
Other |
6 |
8.5% |
2 |
4.9% |
4 |
16.0% |
0.279 |
Y |
| |
Unknown |
2 |
2.8% |
1 |
2.4% |
1 |
4.0% |
0.703 |
Y |
| Site |
Nodular |
1 |
1.4% |
0 |
0.0% |
1 |
4.0% |
0.801 |
Y |
| |
Extranodular |
45 |
63.4% |
28 |
68.3% |
12 |
48.0% |
0.102 |
|
| |
Both |
21 |
29.6% |
11 |
26.8% |
10 |
40.0% |
0.265 |
|
| |
Unknown |
4 |
5.6% |
2 |
4.9% |
2 |
8.0% |
0.987 |
Y |
| PCNS |
Yes |
27 |
38.0% |
18 |
43.9% |
6 |
24.0% |
0.103 |
|
| EBV |
Positive |
52 |
73.2% |
35 |
85.4% |
12 |
48.0% |
0.001 |
|
| KSHV |
Positive |
6 |
8.5% |
5 |
12.2% |
1 |
4.0% |
0.495 |
Y |
| Cause of death |
Yes |
50 |
70.4% |
33 |
80.5% |
16 |
64.0% |
0.137 |
|
| All KS cases |
|
38 |
|
22 |
|
10 |
|
|
|
| Site |
Skin |
32 |
84.2% |
19 |
86.4% |
9 |
90.0% |
0.410 |
|
| |
GI tract |
27 |
71.1% |
15 |
68.2% |
8 |
80.0% |
0.705 |
|
| |
Lung |
21 |
55.3% |
11 |
50.0% |
6 |
60.0% |
0.799 |
|
| |
Lymph node |
20 |
52.6% |
13 |
59.1% |
6 |
60.0% |
0.502 |
|
| |
Other |
16 |
42.1% |
0 |
0.0% |
0 |
0.0% |
0.787 |
Y |
| Cause of death | Yes | 11 | 29.0% | 7 | 31.8% | 2 | 20.0% | 0.791 | Y |
NHL, Non-Hodgkin lymphoma; DLBCL, diffuse large B-cell lymphoma; BL, Burkitt lymphoma; PEL, primary effusion lymphoma; PBL, plasmablastic lymphoma; PCNS, primary central nervous system lymphoma; EBV, Epstein–Barr virus; KSHV, Kaposi sarcoma-associated herpes virus; KS, Kaposi sarcoma; GI, gastrointestinal. P values were calculated by Chi-square test. Y indicates the use of Chi-square test with Yates correction. Bold font indicates statistical significance.