Table 1.
Baseline characteristics of women with and without a diagnosis of endometrial cancer (Total = 79,166)
| Variables | Women with endometrial cancer (N=628) |
Women without endometrial cancer (N=78,538) |
|---|---|---|
| Age (years)* | ||
| Mean (SD) | 54.4 (15.7) | 55.0 (22.6) |
| Median (range) | 55 (16–95) | 55 (1–100) |
| Country | ||
| Canada | 277 (44.1) | 30,842 (39.3) |
| Australia | 82 (13.1) | 14,926 (19.0) |
| United States | 269 (42.8) | 32,770 (41.7) |
| Race | ||
| Caucasian | 129 (20.5) | 12,402 (15.8) |
| Others** | 9 (1.5) | 1,023 (1.3) |
| Missing | 490 (78.0) | 65,113 (82.9) |
| Educational status | ||
| Grade 10 or below | 41 (6.53) | 4,218 (5.37) |
| Grade 11–12 | 32 (5.10) | 2,563 (3.26) |
| Vocational and Technical School | 17 (2.71) | 1,057 (1.35) |
| University degree | 39 (6.21) | 4,404 (5.61) |
| Missing | 499 (79.5) | 66,296 (84.4) |
| Family History of endometrial cancer | ||
| No family history | 516 (82.2) | 74504 (94.9) |
| 1 FDR or SDR | 87 (13.8) | 3709 (4.7) |
| ≥2 FDR or SDR | 25 (4.0) | 325 (0.4) |
| Family History of colorectal cancer | ||
| No family history | 120 (19.1) | 17,784 (22.6) |
| 1 FDR or SDR | 334 (53.2) | 42,598 (54.2) |
| ≥2 FDR or SDR | 174 (27.7) | 18,156 (23.1) |
| Cigarette smoking | ||
| Never | 79 (12.6%) | 7,973 (10.2%) |
| Ever | 59 (9.4%) | 5,111 (6.5%) |
| Missing | 490 (78.0) | 65,454 (83.3) |
| Age at menarche (years) | ||
| Mean (SD) | 12.6 (2.49) | 12.9 (1.57) |
| <12 | 30 (4.8) | 1,428 (1.8) |
| ≥12 to <15 | 63 (10.0) | 5,951 (7.6) |
| ≥15 | 7 (1.1) | 1,217 (1.6) |
| Missing | 528 (84.1) | 69,942 (89.0) |
| Menopausal status | ||
| Premenopausal | 2 (0.3) | 155 (0.2) |
| Postmenopausal | 87 (13.9) | 4,254 (5.4) |
| Missing | 539 (85.8) | 74,129 (94.4) |
| Age at menopause (years) | ||
| Mean (SD) | 41.2 (10.3) | 38.2 (10.4) |
| ≤50 | 75 (11.9) | 3162 (4.0) |
| >50 to ≤55 | 6 (1.0) | 706 (0.9) |
| >55 | 4 (0.6) | 147 (0.2) |
| Missing | 543 (86.5) | 74,523 (94.9) |
| Hormone replacement therapy users | ||
| Never | 86 (13.7) | 9,480 (12.1) |
| Ever | 43 (6.8) | 2,292 (2.9) |
| Missing | 499 (79.5) | 66,766 (85.0) |
| Estrogen only users | ||
| Never | 6 (1.0) | 689 (0.9) |
| Ever | 36 (5.7) | 1,482 (1.9) |
| Missing | 586 (93.3) | 76,367 (97.2) |
| Progesterone users | ||
| Never | 30 (4.8) | 1,166 (1.5) |
| Ever | 11 (1.7) | 974 (1.2) |
| Missing | 587 (93.5) | 76,398 (97.3) |
| Anti-estrogen use status | ||
| Never | 87 (13.9) | 7,740 (9.9) |
| Ever | 5 (0.8) | 233 (0.3) |
| Missing | 536 (85.3) | 70,565 (89.8) |
| Pregnancy | ||
| Never | 10 (1.6) | 2,142 (2.7) |
| Ever | 130 (20.7) | 11,362 (14.5) |
| Missing | 488 (77.7) | 65,034 (82.8) |
| Body mass index (kg/m2) at age 20 | ||
| Mean (SD) | 22.3 (4.65) | 21.8(5.10) |
| <25 | 80 (12.7) | 7,228 (9.2) |
| ≥25 to <30 | 13 (2.1) | 754 (1.0) |
| ≥30 | 4 (0.6) | 302 (0.4) |
| Missing | 531 (84.6) | 70,254 (89.4) |
| Recent body mass index (kg/m2) | ||
| Mean (SD) | 28.5 (6.6) | 25.7 (5.70) |
| <25 | 32 (5.1) | 4,128 (5.2) |
| ≥25 to <30 | 26 (4.1) | 2,011 (2.6) |
| ≥30 | 31 (5.0) | 1,402 (1.8) |
| Missing | 539 (85.8) | 70,997 (90.4) |
| Diabetes (both Type I and Type II) | ||
| Never | 85 (13.5) | 8,273 (10.5) |
| Ever | 16 (2.6) | 496 (0.6) |
| Missing | 527 (83.9) | 69,769 (88.8) |
*
Age at diagnosis for women with endometrial cancer and last known age for women without endometrial cancer.
**
Other races included African American, Latino, Hispanic, Mexican American, Mexican, Cuban, Puerto Rican, Japanese, Chinese, Filipino, Malay, Indonesian, Korean, South Asian, Native American, Polynesian, Micronesian, Australian aboriginal, Melanesian, Caribbean Black, Central/South American, Black African, North African, Middle Eastern and others.
SD, standard deviation.