Table 1.
Drugs that Exhibit High Selectivity and Preference to Oncology Targets
| Drug Name | Total Cancer targets |
Total Approved Drugs targets |
CSI | Targets |
|---|---|---|---|---|
| Isoetharine | 4 | 1 | 4 | β1 adrenergic receptor |
| Salbutamol | 3 | 1 | 3 | β1,2 adrenergic receptor |
| Guanadrel sulfate |
2 | 1 | 2 | Sodium-dependent noradrenaline transporter |
| Diatrizoate | 4 | 2 | 2 | N/A |
| Rimantadine | 2 | 1 | 2 | Influenza A virus matrix protein 2 |
| Starvudine | 2 | 1 | 2 | HIV1 reverse transcriptase |
| Phensuximide | 2 | 1 | 2 | N/A |
| Diethylpropion | 8 | 4 | 2 | Sodium-dependent noradrenaline and dopamine transporters |
| Bromfenac | 12 | 6 | 2 | COX1, 2 |
| Methyprylon | 2 | 1 | 2 |
γ-aminobutyric acid receptor subunit alpha- 1 |
| Iophendylate | 2 | 1 | 2 | N/A |
| Methsuximide | 10 | 5 | 2 | Voltage-dependent T-type calcium channel |