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. Author manuscript; available in PMC: 2015 Mar 4.
Published in final edited form as: Mol Biosyst. 2014 Jan 9;10(3):581–591. doi: 10.1039/c3mb70503j

Table 2.

Top FDA-Approved Drugs with the Highest Betweenness and Degree Obtained from a Network Analysis of the Data

Name Betweenness Degree Indication
Tacrine 2027 348 Alzheimer’s
Sulfisoxazole 1896 310 Antibacterial
Adapalene 905 376 Acne
Flurbiprofen 786 293 Inflammation and Pain
Naftifine 651 367 Antifungal
Conjugated Estrogens 622 360 -
Nilotinib 593 355 leukemia
Proflavine 590 359 bacteriostatic
Bexarotene 571 374 Cancer including lung
Tolcapone 531 349 Parkinson