Table 2.
Biochemical determinations in plasma and RBCs.
| Plasma | RBC | |||||
|---|---|---|---|---|---|---|
| MVA (n = 25) | CAD (n = 22) | Ctrl (n = 20) | MVA (n = 25) | CAD (n = 22) | Ctrl (n = 20) | |
| Arg | 74.22 [69.15–87.08] |
82.88 [64.81–95.74] |
84.80 [73.13–98.01] |
7.57 [5.00–9.53] |
8.64 [5.31–10.48] |
6.84 [3.86–7.80] |
| Cit | 27.45 [24.21–31.16] |
27.61 [20.41–33.83] |
26.55 [24.13–30.68] |
11.36 [9.58–12.35] |
10.48 [8.36–12.11] |
8.37 [7.04–10.78] |
| Orn | 47.66 [41.19–54.11] |
51.82#
[48.72–61.68] |
40.84 [34.09–46.08] |
39.48 [29.52–49.06] |
42.59 [36.74–44.90] |
33.93 [23.77–43.07] |
| ADMA | 0.51#
[0.43–0.60] |
0.49#
[0.45–0.59] |
0.41 [0.35–0.47] |
0.18#
[0.14–0.27] |
0.20#
[0.15–0.25] |
0.15 [0.12–0.20] |
| SDMA | 0.47 [0.42–0.60] |
0.54 [0.45–0.63] |
0.42 [0.36–0.48] |
0.13##
[0.09–0.16] |
0.13#
[0.12–0.15] |
0.10 [0.06–0.11] |
| MMA | 0.12 [0.09–0.13] |
0.11 [0.08–0.13] |
0.12 [0.10–0.14] |
0.13* [0.07–0.18] |
0.05 [0.04–0.09] |
0.09 [0.05–0.12] |
| Arg bioavailability | 1.06#
[0.90–1.26] |
1.01#
[0.87–1.22] |
1.25 [1.04–1.41] |
0.13 [0.11–0.19] |
0.16 [0.12–0.19] |
0.14 [0.09–0.20] |
| Orn/Cit ratio | 1.74 [1.42–2.21] |
1.97###
[1.69–2.40] |
1.48 [1.36–1.71] |
3.88* [3.10–4.41] |
3.96 [3.51–5.03] |
3.92 [3.20–4.32] |
Quantitative variables are expressed as median [interquartile interval]. *P < 0.05 versus CAD; # P < 0.05, ## P < 0.01, and ### P < 0.001 versus Ctrl adjusted for age and gender after log-transformation of the data.