. Author manuscript; available in PMC: 2014 May 11.

Published in final edited form as: Foot Ankle Int. 2013 Jan 14;34(3):351–358. doi: 10.1177/1071100712467980

Table 2.

Objective signs of severe infection Severe infection defined as ≥ 2 of the following

Temperature > 38° Celsius or < 36° Celsius

Heart rate > 90 beats/minute

Respiratory rate >20 beats/minute

White blood cell count > 12,000 cell/mm³

<4000 cells/mm³

Systolic blood pressure <90

Hyperglycemia (serum glucose >200 mg/dl)

Prerenal azotemia (Bun/Creatinine ratio >20)

Metabolic acidosis

CO² < 22 mmol/l and anion gap > 15 mEq/L