A, Clinical traits and vibratory challenge results independantly and significantly associated with inherited elevations in basal serum tryptase; Fisher’s exact test. B, Relative difference of CD203c MFI in affected individuals normalized to paired controls, as a percent of paired control MFI, ((Patient-Control)/Control)*100). C, Difference in %CD63+ within the CD203c+ population of affected individuals, from paired controls. Data in C and D are plotted with median ± interquartile range. *P<0.05 **P<0.01 ***P<0.005; Wilcoxon-signed rank test.