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. Author manuscript; available in PMC: 2014 Sep 24.
Published in final edited form as: Nat Commun. 2014 Mar 24;5:3469. doi: 10.1038/ncomms4469

Figure 2. Mutations in epigenetic regulators occur in 25% of B-ALL patients at diagnosis, including SETD2.

Figure 2

Matched diagnosis and remission sample pairs from 60 pediatric B-ALL patients were baited with target hybrid capture, Illumina sequenced and somatic mutations were identified. Patients are organized by those that eventually relapsed (on the left), and those that did not (on the right). Final risk category and molecular subtypes listed below. MLL: MLL rearranged, HYPO: Hypodiploidy, iAMP21: intrachromosomal amplification of chromosome 21, HYPER: Hyperdiploidy.

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