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Assessment of (A) circular standard deviation (CSD) and (B) the apparent birefringence (Bapp) throughout fatigue life and healing at 0.1 N. Together, these results demonstrate that the newly deposited matrix is highly disorganized throughout the specimen fatigue life. Final specimen cohorts ranged from N=4–10 specimens, since some specimens in the earlier time points were not able to withstand the fatigue testing protocol.
