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. Author manuscript; available in PMC: 2014 May 12.
Published in final edited form as: Curr Opin Oncol. 2014 Jan;26(1):92–99. doi: 10.1097/CCO.0000000000000035

Figure 2. Amino acid catabolism during tumor progression, regression and relapse.

Figure 2

Amino acid catabolism increases during tumor formation, and correlates with increased local inflammation and cancer-associated morbidities. Therapeutic interventions modify local inflammation to break tumor tolerance and reduce amino acid catabolism and co-morbidities, while relapse correlates with the return of processes linked to cancer.