Skip to main content
. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Clin Cancer Res. 2014 Feb 28;20(9):2433–2444. doi: 10.1158/1078-0432.CCR-13-2617

Figure 4. Regulatory T cells (Treg) in the peripheral blood and phenotype of dendritic cells.

Figure 4

(a) Treg were defined as CD4+CD39+CD25+ cells by flow cytometry, which are regularly identified as a defined population. (b) Percentages of CD4+CD39+CD25+ Treg in the peripheral blood of patients (n=16) before and after vaccination. Wilcoxon paired signed-rank test **p = 0.006. (c) Absolute numbers of CD4+CD39+CD25+ Treg in the peripheral blood of patients (n=16) before and after vaccination. Wilcoxon paired signed-rank test **p = 0.005. (d) The frequency of Treg in the peripheral circulation inversely correlates to the absolute number of CD4+ T cells (R2 = −0.6, p < 0.01). Upper and lower lines denote 95% confidence interval.