. 2014 Apr 18;5(2):80–88. doi: 10.5312/wjo.v5.i2.80

Table 3.

Overview of advantages and disadvantages of various scaffolds

Cells	Material	Results
Chondrocyctes	Poly(epsilon-caprolactone)-block-poly(L-lactide)	Applicable for cartilage tissue engineering
Rabbit marrow mesenchymal stem cells	Oligo(poly(ethylene glycol) fumarate) with encapsulated cells and gelatin microparticles loaded with TGF-β1	Maintained viability of cells for 14 d
Rabbit marrow mesenchymal stem cells		Differentiation of cells into chondrocyte-like cells
Chondrocytes	Gelatin microparticle aggregates, +/- TGF-β1	Supported viability and function of chondrocytes
Chondrocytes	Gelatin microparticle aggregates, +/- TGF-β1	Applications in cartilage-engineering
Human adipose derived stem cells	Genipin-crosslinked cartilage derived matrix	Using genipin resulted in contraction free biomaterial.
Human adipose derived stem cells	Genipin-crosslinked cartilage derived matrix	Chondrogenesis
Human mesenchmal stem cells	Poly(epsilon-caprolactone)	Cell colonization, proliferation and osteogenic differentiation were related to the micro-architecture of the pore structure
Human chondrocytes	Blend of poly (lactic-co-glycolic acid) and polyvinyl alcohol	Supported cell adhesion and growth
Human chondrocytes		After implantation, there was better bone in-growth and bone formation inside the scaffold.
Bone marrow stem cells	Polyglycolic acid, poly (lactic acid)	Cell infiltrated the scaffold
		Good cellular compatibility
		Applicable to repair craniomaxillofacial bone defects

TGF: Transforming growth factor.