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. Author manuscript; available in PMC: 2014 May 12.
Published in final edited form as: Cell Metab. 2014 Jan 7;19(1):96–108. doi: 10.1016/j.cmet.2013.12.003

Figure 7. Integration of human genetic and transcriptional data highlights a role for PGC-1α in BAIBA generation.

Figure 7

A) A table of the transcriptional changes in genes associated with the BAIBA biosynthesis pathway in primary myocytes expressing PGC-1α as assessed by expression arrays (left panel). Right panel includes genes in the BAIBA biosynthesis pathway and the significance of their relationship to BAIBA plasma concentrations in the Framingham Heart Study (FHS). B) The BAIBA biosynthesis pathway annotated with the genes increased by forced PGC-1α expression in primary myocytes or identified by the GWAS study.