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. Author manuscript; available in PMC: 2014 May 12.
Published in final edited form as: Lab Invest. 2012 Sep 10;92(11):1541–1552. doi: 10.1038/labinvest.2012.125

Table 1. Granuloma formation and M. avium dissemination in HO-1-/- and HO-1+/+ mice.

Test/Parameter HO-1-/- (n=8) HO-1+/+ (n=8)
Granuloma size 29 ± 10 μm 1100 ± 102 μm
Granuloma number 3 ± 1 16 ± 5
Morphometric index 1 ± 0.5 10 ± 0.2
M. avium dissemination (to liver, spleen) cultures positive cultures negative
Mortality 50% by 6 weeks None by 6 weeks