Table 1.
Clinical spectrum of celiac disease and gluten sensitivity
| Symptoms | Serology | histology | Treatment | |
|---|---|---|---|---|
| Typical Celiac | Malabsorption Syndrom and Diarrhoea | Positive in 99-100% | Marsh IIIb-c rarely Marsh IIIa | Gluten free diet (GFD) |
| Atypical Celiac | GI and non GI symptoms | Positive only in 40-70% | Marsh 0-IIIc | Observation and or GFD |
| Refractory Celiac | Malabsorption Syndrom and Diarrhoea | 90-100% | Marsh IIIa-IIIc | GFD and Immunomodulator |
| Gluten sensitivity | Typical and/or atypical symptoms | Negative | minimal or normal mucosal changes | Gluten free diet |