Figure 8.

Secondary structure predictions of (a) hβ₂m and (b) ΔN6 in their fibril forms based on TALOS+ analysis of assigned chemical shifts. TALOS+ predicted backbone dihedral angles (phi, blue squares, psi, red circles), with error bars based on the 10 best database matches. The predicted secondary structures are shown at the top of (a) and (b) (β-strands, filled boxes; turn or loop, curved lines; not assigned, dashed line). The white box in (a) depicts the seven residues present in the spectrum of INEPT-based J-TOBSY.⁹⁴