Table 1.
Baseline demographics and clinical characteristics of subjects
| Demographic/anthropometric data | ||
| Age (years) | 72 ± 10 | |
| Gender (# female/male) | 13/1 | |
| Weight (kg) | 94 ± 30 | |
| BMI (kg/m2) | 35.5 ± 7.9 | |
| Baseline clinical characteristics | n (%) | Comments |
| B-type natriuretic peptide (pg/mL) | 142 ± 33 | |
| Six minute walk distance (m) | 313 ± 86 | |
| Hypertension | 14 (100%) | No known secondary causes |
| Coronary artery disease | 5 (36%) | 1 with prior CABG, 1 with prior PCI |
| Diabetes mellitus | 6 (43%) | All type II; Hgb A1c = 6.8 ± 0.8% |
| Chronic kidney disease | 14 (100%) | eGFR = 60 ± 17 ml/min/1.73 m2 |
| NYHA class II/III | 2 (14%)/12 (86%) | |
| Prior heart failure hospitalization | 10 (71%) | |
| On chronic loop diuretic therapy | 11 (79%) | |
Abbreviations: BMI: body mass index; CABG: coronary artery bypass grafting; NYHA: New York Heart Association; eGFR: estimated glomerular filtration rate per Modification of Diet in Renal Disease; PCI: percutaneous coronary intervention