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Rifampicin resistance-associated mutations detected in M. tuberculosis study isolates
| Gene | N° and type of isolates tested | N° of isolates with indicated genotype | Nucleotide change | Amino acid change |
|---|---|---|---|---|
|
rpoB |
7 RIFR |
5 |
531TCG → TTG |
Ser → Leu |
| 1 |
526CAC → GAC |
His → Asp |
||
| 1 |
516GAC → GTC |
Asp → Val |
||
| 100 RIFS | 1 | 516GAC → TAC | Asp → Tyr |
NA = not applicable; WT = wild type; RIFR = rifampicin resistant isolate; RIFS = rifampicin sensitive isolate, N° = Number.
