Table 1. Scoring of histology fi ndings in the liver33 .
| Steatosis |
1: Mainly macrovesicular, up to 33% of the lobules 2: 33%–66% commonly mixed steatosis 3: 66% (panacinar): commonly mixed steatosis |
| Hepatocyte ballooning |
0: None 1: Occasional, zone 3 2: Obvious, zone 3 3: Moderate to marked, predominantly zone 3 |
| Lobular inflammation |
0: None 1: Scattered PMN, occasional mononuclear cells, 1–2/209 objective 2: PMN associated with ballooned hepatocytes, mild chronic inflammation, 2–4/209 objective 3: Acute and chronic inflammation, PMN may concentrate in zone 3 areas of ballooning, 4/209 objective |
| Portal inflammation |
0: None 1: Mild, some portal areas 2: Mild to moderate, most portal areas 3: Moderate to severe, most portal areas |
| Fibrosis stage |
0: None 1: Zone 3 perivenular, perisinusoidal fibrosis 2: Stage 1 changes + periportal fibrosis 3: Bridging fibrosis 4: Cirrhosis |