Table 3.
Effect of MEMC on the ALT, AST, and ALP (U/L) level following its pretreatment against the PCM-induced hepatic injury.
| Treatment | Dose (mg/kg) | ALT (U/L) | AST (U/L) | ALP (U/L) |
|---|---|---|---|---|
| Normal | — | 36.05 ± 10.52 | 124.3 ± 16.14 | 193.0 ± 41.44 |
| 10% DMSO + PCM | 1714 ± 142.2# | 2266 ± 340.4# | 330.0 ± 42.35# | |
| NAC + PCM | 50 | 884.2 ± 195.4* | 1569 ± 106.4* | 284.3 ± 5.536* |
| MEMC + PCM | 50 | 2734 ± 495.2* | 1292 ± 468.0* | 311.5 ± 25.64 |
| 250 | 1638 ± 174.4 | 2565 ± 170.5 | 359.0 ± 32.73 | |
| 500 | 244.9 ± 101.9* | 526.1 ± 191.1* | 221.7 ± 25.55* |
Values are expressed as means ± SEM of six replicates.
#Significantly different as compared to normal group, P < 0.05.
*Significantly different as compared to negative control (10% DMSO + PCM), P < 0.05.