Table 3.

Univariate and multivariate Cox analyses of the association between the features of the patients and overall survival.

	Univariate Cox regression			Multivariate Cox regression
	HR	95% CI	P	HR	95% CI	P
Age (per year)	1.048	1.029–1.067	<0.001	1.039	1.018–1.061	<0.001
Gender (female versus male)	0.884	0.575–1.361	0.576	∗	∗	∗
Secondary versus primary GBM	0.271	0.123–0.597	0.001	0.487	0.215–1.106	0.086
Resection (total versus others)	0.854	0.559–1.303	0.463	∗	∗	∗
KPS (per 10 points)	0.990	0.979–1.001	0.083	∗	∗	∗
IDH1/IDH2 (mutated versus nonmutated)	0.274	0.124–0.604	0.001	0.237	0.157–0.791	0.011
IDH1 SNP (SNP versus no SNP)	0.745	0.343–1.617	0.456	∗	∗	∗
TP53 (mutated versus nonmutated)	0.764	0.489–1.196	0.240	∗	∗	∗

*Not included in multivariate analysis.

HR: hazard ratio; CI: confidence interval; P: P value; IDH1 SNP refers to rs11554137.