Table 2.
Characteristic | RCC cohort (n = 8,633)
|
Matched comparison cohorta (n = 83,055)
|
||
---|---|---|---|---|
Total number | Percentage (%) | Total number | Percentage (%) | |
Sex | ||||
Female | 3,284 | 38.0 | 31,653 | 38.1 |
Male | 5,349 | 62.0 | 51,402 | 61.9 |
Age at diagnosis/index date, y | ||||
≤59 | 2,554 | 29.6 | 25,415 | 30.5 |
60–69 | 2,488 | 28.8 | 23,967 | 28.9 |
70–79 | 2,417 | 28.0 | 22,586 | 27.2 |
80+ | 1,174 | 13.6 | 11,087 | 13.3 |
Year of cancer diagnosis | ||||
1995–1999 | 2,401 | 27.8 | 23,132 | 27.9 |
2000–2004 | 2,566 | 29.7 | 24,834 | 29.9 |
2005–2010 | 3,666 | 42.5 | 35,089 | 42.2 |
Cancer stage | ||||
Nonmetastatic | 4,732 | 54.8 | – | – |
Metastatic | 2,597 | 30.1 | – | – |
Unknown | 1,304 | 15.1 | – | – |
Comorbidity | ||||
Myocardial infarction | 528 | 6.1 | 4,684 | 5.6 |
Congestive heart failure | 448 | 5.2 | 3,703 | 4.5 |
Peripheral vascular disease | 414 | 4.8 | 3,498 | 4.2 |
Cerebrovascular disease | 723 | 8.4 | 6,576 | 7.9 |
Dementia | 58 | 0.7 | 474 | 0.6 |
Chronic obstructive pulmonary disease | 686 | 7.9 | 6,192 | 7.5 |
CTD | 217 | 2.5 | 1,919 | 2.3 |
Ulcer disease | 446 | 5.2 | 3,888 | 4.7 |
Mild liver disease | 85 | 1.0 | 746 | 0.9 |
Hemiplegia | 13 | 0.2 | 115 | 0.1 |
Moderate to severe renal disease | 265 | 3.1 | 2,068 | 2.5 |
Diabetes type 1 or 2 | 531 | 6.2 | 4,653 | 5.6 |
Diabetes with end-organ damage | 221 | 2.6 | 1,776 | 2.1 |
Any tumor (except RCC) | 930 | 10.8 | 8,539 | 10.3 |
Leukemia | 22 | 0.3 | 155 | 0.2 |
Lymphoma | 50 | 0.6 | 382 | 0.5 |
Moderate to severe liver disease | 33 | 0.4 | 266 | 0.3 |
Metastatic solid tumor (except RCC) | 132 | 1.5 | 1,048 | 1.3 |
AIDS | 3 | 0.0 | 20 | 0.0 |
Charlson comorbidity index score | ||||
0 | 4,980 | 57.7 | 49,170 | 59.2 |
1 | 1,532 | 17.7 | 14,924 | 18.0 |
2–3 | 1,667 | 19.3 | 15,871 | 19.1 |
4+ | 454 | 5.3 | 3,090 | 3.7 |
CTD = connective tissue disease.