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. Author manuscript; available in PMC: 2014 May 12.
Published in final edited form as: Alcohol Clin Exp Res. 2009 Sep 17;33(12):2103–2112. doi: 10.1111/j.1530-0277.2009.01050.x

Table 1.

Genotype Distribution of 5-HTTLPR, OPRM1 A118G, and DRD2 −141C Ins/Del in Controls and Alcoholics

5-HTTLPR n S/S (%) S/L (%) L/L (%)

Controls 338 108 (32.0) 173 (51.2) 57 (16.9)
Alcoholics 365 136 (37.3) 163 (44.6) 66 (18.1)
MAXDRINKS ≤ 22 124 38 (30.6) 61 (49.2) 25 (20.2)
MAXDRINKS 23–35 121 46 (38.0) 56 (46.3) 19 (15.7)
MAXDRINKS ≥ 36 118 51 (43.2) 45 (38.1) 22 (18.6)
OPRM1 A118G n A/A (%) A/G (%) G/G (%)

Controls 338 198 (58.6) 120 (35.5) 20 (5.9)
Alcoholics 365 230 (63.0) 123 (33.7) 12 (3.3)
MAXDRINKS ≤ 22 124 70 (56.5) 48 (38.7) 6 (4.8)
MAXDRINKS 23–35 121 71 (58.7) 47 (38.8) 3 (2.5)
MAXDRINKS ≥ 36 118 88 (74.6) 27 (22.9) 3 (2.5)
DRD2 −141C Ins/Del n Ins/Ins (%) Ins/Del (%) Del/Del (%)

Controls 338 235 (69.5) 97 (28.7) 6 (1.8)
Alcoholics 365 270 (74.0) 84 (23.0) 11 (3.0)
MAXDRINKS ≤ 22 124 93 (75.0) 29 (23.4) 6 (1.8)
MAXDRINKS 23–35 121 82 (67.8) 36 (29.8) 2 (1.6)
MAXDRINKS ≥ 36 118 94 (79.7) 18 (15.3) 3 (2.5)