Figure 1. Increase in type VII collagen (C7) deposition and improvement of clinical symptoms after hematopoietic cell transplantation (HCT) treatment for recessive dystrophic epidermolysis bullosa (RDEB).

Immunofluorescent stain of C7 (red) and 4ʹ-6-diamidino-2-phenylindole (DAPI) (blue) visualizing the dermal-epidermal junction (A) before transplant and (B) 2.5 years after transplant. Photos of an RDEB patient presenting wounds over the back of the hand (C) before transplant and (D) the improvement after transplant.