TABLE III.
Cox Proportional Hazards Regressions
| Patient population | Variable | Hazard of patient death | Hazard of patient tumor progression |
|---|---|---|---|
| Full populationa (n = 51) | Neurosphere formation | 16.6, CI (1.93–142); P-value <0.010 | 9.94, CI (2.91–34.0); P-value <0.001 |
| Glial tumorsb (n = 27) | Neurosphere formation | 5.06 (NS), CI (0.48–53.4); P-value <0.177 | 6.62, CI (1.70–25.8); P-value 0.006 |
| Embryonalc (n = 12) | Neurosphere formation | >10, CI (>10 to >10) P-value <0.001 | >10, CI (>10 to >10); P-value <0.001 |
| Medulloblastomad (n = 7) | Neurosphere formation | >10, CI (>10 to >10); P-value <0.001 | >10, CI (>10 to >10); P-value <0.001 |
CI, 95% confidence interval; NS, not significant.
a
Mean age 8.4 years, 20/51 tumors with neurosphere formation.
b
Mean age 8.47 years, 9/27 tumors with neurosphere formation.
c
Mean age 5.56 years, 7/12 tumors with neurosphere formation.
d
Mean age 4.71 years, 4/7 tumors with neurosphere formation.