Table 2.
Heart weight, blood pressure and ventricular function
| Control | AngII | AngII+A779 | |
|---|---|---|---|
| Heart/body weight, mg/g | 2.93±0.03 | 3.35±0.08* | 3.51±0.11* |
| Blood pressure, mm Hg | 115±5.5 | 182±9.5* | 178±5.8* |
| Ejection fraction, % | 66.8±3.4 | 60.6±3.5 | 61.5±3.1 |
| Fraction shortening, % | 36.5±2.6 | 37.8±3.2 | 34.7±2.8 |
| Average wall thickness, mm | 2.0±0.1 | 2.2±0.1 | 2.2±0.1 |
| Mitral valve E:A | 1.4±0.1 | 1.4±0.1 | 1.2±0.1 |
Abbreviation: AngII, angiotensin II.
*P < 0.05 vs. control.