Table I.

Effect of T3 on selected angiogenic growth factor secretion by first trimester stromal-depleted (CD10−) and stromal-enriched (CD10+) cells

	T3 (nM)	Angiogenin	Ang-2	VEGF-A
CD10−		N = 5	N = 4	N = 5
	0	1	1	1
	1	1.1 ± 0.2	2.7 ± 1.3*	1.8 ± 0.8
	10	1.1 ± 0.3	1.2 ± 0.1	1.8 ± 0.8
	100	1.2 ± 0.4	0.9 ± 0.1	1.6 ± 0.7
CD10+		N = 6	Above limit	N = 6
	0	1		1
	1	1.1 ± 0.1		1.0 ± 0.1
	10	1.1 ± 0.1		1.0 ± 0.1
	100	1.2 ± 0.2		1.2 ± 0.2

Data are normalized to 0 nM within each experiment and presented as mean ± SEM.

Ang-2 concentrations in CD10+ cells and fibroblast growth factor basic (FGF-basic), tissue inhibitor of metalloproteinase I (TIMP-1), intracellular adhesion molecule 1 (ICAM-1) concentrations in both CD10− and CD10+ cells were above the manufacturer's standard curve limit. Platelet-derived growth factor-BB (PDGF-BB) was below the detection limit in all samples and keratinocyte growth factor (KGF) was only detectable in two or less samples per experimental set.

Ang-2, Angiopoietin-2; VEGF-A, vascular endothelial growth factor-A.

*P<0.05 compared with no T3 treatment (0 nM).