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. 2011 Jul 29;2(10):729–734. doi: 10.1021/ml200087m

Table 3. Inhibition of Yeast Pol II, Malate Dehydrogenase, and Chymotrypsin by 813.

  % inhibition ± SDa
compd yeast Pol II malate dehydrogenase chymotrypsin
8 14.7 ± 5.0 0.5 ± 0.5 0.0 ± 0.0
9 9.3 ± 2.0 1.4 ± 1.1 0.6 ± 0.4
10 17.6 ± 3.3 0.6 ± 0.4 1.8 ± 1.4
11 12.0 ± 3.1 0.0 ± 0.0 0.0 ± 0.0
12 10.5 ± 4.2 0.0 ± 0.0 0.1 ± 0.1
13 5.2 ± 3.6 0.0 ± 0.0 1.5 ± 1.5
a

Percentage inhibition at 100 μM.