Table 3. Inhibition of Yeast Pol II, Malate Dehydrogenase, and Chymotrypsin by 8–13.
% inhibition ± SDa |
|||
---|---|---|---|
compd | yeast Pol II | malate dehydrogenase | chymotrypsin |
8 | 14.7 ± 5.0 | 0.5 ± 0.5 | 0.0 ± 0.0 |
9 | 9.3 ± 2.0 | 1.4 ± 1.1 | 0.6 ± 0.4 |
10 | 17.6 ± 3.3 | 0.6 ± 0.4 | 1.8 ± 1.4 |
11 | 12.0 ± 3.1 | 0.0 ± 0.0 | 0.0 ± 0.0 |
12 | 10.5 ± 4.2 | 0.0 ± 0.0 | 0.1 ± 0.1 |
13 | 5.2 ± 3.6 | 0.0 ± 0.0 | 1.5 ± 1.5 |
Percentage inhibition at 100 μM.