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. 2011 Apr 5;2(6):485–487. doi: 10.1021/ml200039u

Figure 2.

Figure 2

Details of [1H−15N] HSQC showing resonances of residue Phe67 of [15N]-CypA in the CypA−Alisporivir, CypA−EthV4Cs, or CypA−MeV4Cs complexes. Superimposed are the 1D projection. Experiments were performed as in Figure 1. [15N]-CypA was incubated for 15 h with a mixture of 1:1 Alisporivir:EthV4Cs (left spectrum) or Alisporivir:MeV4Cs (right spectrum) dried in 5 mm NMR tubes.