Table 2. Speciation of Radioactivity in Brain and Blood of Mice Injected with [18F]8 and [11C]1a (% Intact Tracera).
blood |
brain |
|||
---|---|---|---|---|
tissue | 10 min | 30 min | 10 min | 30 min |
[18F]8 | 12 ± 3 | 5 ± 4 | 92 ± 4 | 88 ± 6 |
[11C]1a | 20 ± 5 | 11 ± 2 | 96 ± 1 | 92 ± 3 |
The extraction efficiency from the blood and brain homogenate samples was 64–95%.