Table 1. IC50 Values for Inhibition of CE Transfera.
IC50 values were determined using a standard bioassay described in ref (10). The IC50 value for torcetrapib was been determined by this method in ref (7a) and was reported to be 13 nM.
Average of three or more 10 point titrations.
Result of a single 10 point titration.
Average of two 10 point titrations.
Inactive indicates <50% inhibition of CETP at a concentration of 100 μM.