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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: Clin Cancer Res. 2013 Dec 23;20(7):1946–1954. doi: 10.1158/1078-0432.CCR-13-1959

Table 2. 2- and 5- Year Recurrence Free Survival Rates and Overall Survival Rates by Stage and Biomarker Groups.

Variable RFS(95% CI) OS (95% CI)
2-year 5-year 2-year 5-year
Stage I 74% (69%, 80%) 54% (48%, 61%) 87% (82%, 91%) 68% (62%, 75%)
II 57% (47%, 70%) 35% (25%, 48%) 83% (74%, 92%) 51% (41%, 64%)
III 41% (30%, 55%) 24% (15%, 38%) 57% (46%, 71%) 44% (33%, 59%)
m-Insulin receptor 0 70% (64%, 76%) 48% (42%, 55%) 84% (79%, 89%) 62% (56%, 70%)
Positive 58% (50%, 66%) 40% (33%, 49%) 76% (69%, 83%) 58% (50%, 66%)
c-pAMPK 0 55% (47%, 65%) 33% (25%, 44%) 77% (70%, 86%) 52% (43%, 62%)
Positive 69% (64%, 75%) 50% (44%, 57%) 82% (78%, 87%) 64% (59%, 71%)
c-pmTOR 0 53% (44%, 65%) 34% (25%, 45%) 69% (60%, 80%) 48% (38%, 60%)
Positive 69% (64%, 74%) 49% (43%, 55%) 84% (80%, 89%) 65% (59%, 71%)
c-CXCR2 <Median 70% (63%, 77%) 49% (42%, 57%) 83% (78%, 89%) 66% (60%, 74%)
>=Median 61% (54%, 68%) 41% (35%, 49%) 78% (73%, 85%) 55% (48%, 63%)
c-EPCAM 0 58% (50%, 67%) 39% (31%, 48%) 76% (69%, 84%) 51% (43%, 61%)
Positive 69% (63%, 75%) 49% (43%, 56%) 84% (79%, 89%) 66% (60%, 73%)
n-FEN1 <Median 69% (63%, 77%) 50% (43%, 58%) 85% (80%, 91%) 68% (62%, 76%)
>=Median 61% (54%, 68%) 41% (34%, 49%) 76% (70%, 83%) 54% (47%, 62%)