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. 2014 May 12;9(5):e97513. doi: 10.1371/journal.pone.0097513

Figure 1. Sensitivity and false positive rate.

Figure 1

The figure summarizes mean sensitivity (red solid line, left axis) and false positive rate (blue dash line, right axis) for ICDMR, QDMR, t-test and WRST. The mean difference of methylation intensities between methylated and unmethylated groups is 2 (i.e., E = 2). The proportion of probes residing in the DMRs is 0.2. At the indicated MF, mean sensitivity and false positive rate are calculated given the correlation between neighboring probes being 0 (ρ = 0), 0.3 (ρ = 0.3), 0.5 (ρ = 0.5) and 0.7 (ρ = 0.7), respectively. Different MF values are indicated on the x-axis.