Table 1.
Biopsy results | Previously negative biopsy (%) | Active surveillance (%) | P-value |
---|---|---|---|
% Positive |
27/78 (34.6%) |
42/49 (85.7%) |
0.0001 |
% Positive in AZ |
17/78 (21.8%) |
17/49 (34.7%) |
0.1492 |
% TZ involved |
8/78 (10.3%) |
5/49 (10.2%) |
1 |
% AZ only |
1/78 (1.3%) |
2/49 (4%) |
0.56 |
% AZ findings changed risk stratification |
3/78 (3.8%) |
3/49 (6.1%) |
0.68 |
% Only TZ |
0/78 (0%) |
0/49 (0%) |
1 |
% Cores involved |
4.5/26 (17.3%) |
3.1/26 (11.9%) |
0.0423 |
Clinically insignificant cancer* |
10/27 (37%) |
25/49 (51%) |
0.3366 |
Gleason ≥ 7 anywhere |
12/27 (44.4%) |
12/49 (24.5%) |
0.1215 |
Gleason ≥ 7 in AZ |
9/27 (33.3%) |
5/49 (10.2%) |
0.0273 |
TRUS results |
|
||
Hypoechoic lesion anywhere |
26/78 (33.3%) |
12/49 (24.5%) |
0.3248 |
Hypoechoic lesion in AZ |
8/78 (10.3%) |
0/49 (0%) |
0.0228 |
Hypoechoic lesion in AZ + Cancer in AZ | 5/78 (6.4%) | 0/49 (0%) | 0.1555 |
*Gleason 6(3 + 3), ≤ 3 cores, ≤ 50% of any core positive.