Skip to main content
. 2014 May 12;9(5):e97087. doi: 10.1371/journal.pone.0097087

Figure 5. Comparison of RF, anti-CCP and anti-dsDNA autoantibodies levels in plasma among the study groups.

Figure 5

Levels of rheumatoid factor (RF) determined by kinetic nephelometry (A), anti-cyclic citrullinated peptide (anti-CCP) (B) and anti-doubled stranded DNA (anti-dsDNA) (C) determined by a fluorescence enzyme immunoassay (EliA test) in patients diagnosed with RA (A and B) (n = 11) or with SLE (C) (n = 7) (some patients had both diagnoses). Solid lines and error bars denote the median and interquartile range, respectively. The dotted lines correspond to the clinical limits below which a sample is considered negative according to the technique used for its detection (RF: <20 IU/mL, anti-CCP: <7 U/mL and anti-dsDNA: <10 IU/mL). Differences between HV and patients prior-RTX were evaluated with Mann–Whitney tests and between patients prior-RTX and patients after-RTX with Wilcoxon tests. All p values reported are 2-tailed.