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miR-17-5p inhibited the luciferase activity of the wild-type MAP3K8 3′UTR construct (right), whereas no decrease in activity was observed in cells co-transfected with the mutant MAP3K8 3′UTR construct (left) or mock plus wild-type or mutant construct (right and left, respectively). Bars indicate the means of three independent experiments, and the error bars indicate standard deviations. **p<0.001 compared with controls.
