Table 4. mRNA expression analysis of selected cytokines and fatty acid metabolic proteins from tissue isolated from chow/HFD-fed Alb-Cre PTEN^f/f mice.

Table 4 mRNA analysis of selected genes		Alb-Cre			PTENf/f			P value
inflammation	Chow		HFD	Chow		HFD	vs genotype	vs HFD	Interaction
TNFα	0.02±0.14a		0.11±0.16c	0.41±0.14a		0.48±0.12c	0.023	0.605	0.974
CD14	0.09±0.09a		0.17±0.11b	0.41±0.09a		0.36±0.08b	0.018	0.862	0.521
IL-6	0.07±0.06		0.08±0.05	0.12±0.05		0.05±0.05	0.964	0.616	0.541
IL-10	0.02±0.01		0.03±0.01	0.03±0.01		0.01±0.01	0.794	0.955	0.118
lipid transport and metabolism
PPARα	0.02±0.02a,b		0.07±0.02b	0.04±0.02a,c		0.08±0.12c	0.419	0.034	0.664
PPARγ	0.51±0.64a		0.76±0.74b	5.48±0.58a		6.41±0.58b	<0.001	0.374	0.609
CD36	0.01±0.02a		0.02±0.02b	0.11±0.01a,c		0.18±0.01b,c	<0.001	0.055	0.241
FATP2	0.30±0.11a		1.1±0.13a,c	0.40±0.11b		0.60±0.11b,c	0.188	<0.001	0.027

Data are means± SEM as analyzed by two-way ANOVA with a Holm-Sidak post hoc analysis (Alb-Cre group compared to PTEN^f/f group).

Values are mean (SEM); statistical analysis performed by two-way ANOVA followed by Holm-Sidak analysis.

Letter with similar superscripts (a, b, c) denote significant difference of P<0.05.