Table 3. The IL-6 plasma concentration (mmol/L) in untreated controls, Sham and CPB groups Vehicle and treated with FTY-720 after 1 hour and 24 hours recovery period.
Group | 1 hour recovery | 24 h recovery |
Healthy controls | Not detected | – |
Sham-Vehicle | 2.8 ± 2.2 | 5.7 ± 3.3 |
CPB-Vehicle | 4449 ± 589 | 2.7 ± 1.8 |
Sham FTY-720 | 4.6 ± 2.2 | 5.6 ± 5.6 |
CPB FTY-720 | 3793 ± 593a | 9.1 ± 5.2 |
Abbreviations: CPB, cardiopulmonary bypass; 24 h, scarification at 24 h later the end of the extracorporeal circulation.
a- p<0.05 vs CPB, t-test.