Table 3. Comparison of results of compositional or gene expression analysis from previous studies evaluating differences between ACL and PT or differences between male and female PT to quantitative results from the current study.
Comparison & Method | Gene/Protein Name | Result | Current Study | Reference |
Rabbit ACL vs PT | Fibronectin | ACL>PT | + | [8] |
Protein ELISA | ||||
Human ACL vs PT | Type I Collagen | ACL<PT | + | [11] |
Immunohistochemistry | Type III Collagen | ACL>PT | + | |
Type V Collagen | ACL>PT | + | ||
Elastin | ACL>PT | + | ||
Porcine ACL vs PT | COL2A1 | ACL<PT | − ACL = PT | [13] |
Gene Array † | ACAN | ACL>PT | + | |
MYOC | ACL<PT | − ACL = PT | ||
COMP | ACL>PT | + | ||
FMOD | ACL<PT | + | ||
TSP4 | ACL<PT | + | ||
TNC | ACL>PT | − ACL>PT | ||
Human Male vs Female PT | COL3A1 | Female>Male | − Male>Female | [14] |
Gene Expression | COL1A1 | Female = Male | +/− Female>Male | |
DCN | Female = Male | +/− Female>Male | ||
BGN | Female = Male | +/− Male>Female | ||
FMOD | Female = Male | + | ||
MMP3 | Male>Female* | Female >Male* |
+ Similar finding or similar trend in current study to previous study. – Different finding or different trend in current study to previous study. +/− Consistent with previous work.
*Trend to significance (≤0.08).
Statistical differences between individual normalized gene expression values not reported in original study.