. 2014 May 12;9(5):e96719. doi: 10.1371/journal.pone.0096719

Table 3. Secondary metabolite biosynthesis gene clusters identified in the genomes of PVA 94-07, GBA 94-10 and J1074 using antiSMASH 2.0.

PVA 94-07	GBA 94-10	S. albus J1074	tnp	Putative product
Gene cluster type	Gene cluster type	Gene cluster type
Nrps1^*	Nrps1^*		+
		T1pks-Nrps1	+
T1pks-butyrolactone^*	T1pks-butyrolactone^*		+
Terpene1	Terpene1
Nrps2	-
Nrps-T3pks-t1pks	Nrps-T3pks-T1pks		+	kijanimycin-related
*Nrps-T1pks*	*Nrps-T1pks*	*Nrps-T1pks*
*Terpene2*	*Terpene2*	*Terpene2*		hopanoids
*Bacteriocin1*	*Bacteriocin1*	*Bacteriocin1*
T1pks1	T1pks1		+
		*Bacteriocin2*
		*Nrps3*
Bacteriocin2	Bacteriocin2
*Siderophore1*	*Siderophore1*	*Siderophore1*
*Terpene3*	*Terpene3*	*Terpene3*
Lantipeptide	-		+
*Terpene4*	*Terpene4*	*Terpene4*
*Thiopeptide-lantipeptide*	*Thiopeptide-lantipeptide*	*Thiopeptide-lantipeptide*
		*Bacteriocin3*	+
		*Nrps4*
Nrps5	Nrps5		+	lipoglycopeptide
Nrps6	Nrps6		+
*Nrps7*	*Nrps7*	*Nrps7*
*Nrps8*	*Nrps8*	*Nrps8*
*Siderophore2*	*Siderophore2*	*Siderophore2*		deferoxamine
Nrps9	Nrps9
*Ectoine*	*Ectoine*	*Ectoine*		ectoine
T2pks	T2pks		+	enterocin
		*Nrps10*		indigoidin
*Terpene5*	*Terpene5*	*Terpene5*	+
*T3pks*	*T3pks*	*T3pks*
*T1pks2*	*T1pks2*	*T1pks2*		candicidin
*Nrps-t1pks-lantipeptide*	*Nrps-t1pks-lantipeptide*	*Nrps-t1pks-lantipeptide*		antimycin
*T1pks3*	*T1pks3*	*T1pks3*	+
T1pks-butyrolactone^*	T1pks-butyrolactone^*		+
Nrps1^*	Nrps1^*		+

Distribution 5′ to 3′ end. Nrps – non-ribosomal peptide synthetase; pks – polyketide synthase (T1-3 = type 1–3); tnp – transposase gene or remnants thereof.

*Duplicated inverted clusters located within chromosomal TIRs. Clusters in J1074 and their homologues in PVA 94-07 and GBA 94-10 are indicated in bold Italic.