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. 2014 May 12;9(5):e97535. doi: 10.1371/journal.pone.0097535

Figure 6. The protocadherin β cluster genes were differentially regulated in SmcHD1 knock-down cells.

Figure 6

A. A number of genes in the protocadherin β cluster were up-regulated in SmcHD1 knock-down SH-SY5Y cells. A graphical representation showing the position of differentially regulated genes on human chromosome 5. Below in red is the corresponding position of the upregulated genes in the protocadherin β cluster (5q31.3) upon loss of SmcHD1. B. mRNA quantitation of selected protocadherin β genes using RT-qPCR in SmcHD1 knock-down SH-SY5Y cells. The copy numbers are relative to and corrected using β-actin cDNA levels. * indicates P-values <0.05, ** P-values <0.01 and *** P-values <0.001 using an unpaired Students t-test.