Table 1. Structural characteristics of nanotrap particles*.
| ID | Core Bait | Matrix | Shell | VSA in Shell | Target |
| NT073 | Cibacron Blue F3GA | NIPAm-Bis-AA | Y | Y | HIV-1 virion, gp41 |
| NT077 | Acrylic Acid | NIPAm-Bis-AAc | Y | N | No binding to Tat |
| NT080 | Reactive Red 120 | NIPAm-Bis-AA | Y | N | Exosomal TAR-RNA, intracellular Nef, p24 |
| NT081 | Cibacron Brilliant Yellow | NIPAm-Bis-AA | Y | N | Minimum binding to Tat |
| NT082 | Cibacron Blue F3GA | NIPAm-Bis-AA | Y | N | Exosomal TAR-RNA, Tat |
| NT083 | Allylamine | NIPAm-Bis-AA | Y | N | Minimum binding to Tat |
| NT084 | Acid Black 48 | NIPAm-Bis-AAc | N | N | Tat, p24 |
| NT085 | Pigment Red | NIPAm-Bis-AAc | Y | Y | No binding to Tat |
| NT086 | Methacrylate | NIPAm-Bis-MA | Y | Y | HIV-1 virion, membrane-associated Nef, gp41, minimum binding to Tat |
*Nanotrap particles are homogenous hydrogel particles of about 700–800 nm in diameter that have a shell made of polymers of N-isopropylacrylamide (NIPAm) and co-monomers such as acrylic acid (AAc), allylamine (AA) and methacrylate (MA) with cross links of N,N'-methylenebisacrylamide (Bis) [37], [54]. Some of these shelled nanotrap particles are also coated with vinyl sulfonic acid (VSA) [38].