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. 2014 May 12;9(5):e96861. doi: 10.1371/journal.pone.0096861

Figure 1. Effects of propofol on MAP, CoBF, and DPOAE.

Figure 1

Following a loading dose of 5/kg, three propofol maintenance doses of 10 mg·kg−1 h−1 (propofol dose 1), 20 mg·kg−1·h−1 (propofol dose 2), and 40 mg kg−1 h−1 (propofol dose 3) were infused for 115 min. A, MAP values. * P<0.05 MAP 20 min after infusion vs B. # P<0.01 MAP 20 min after infusion vs B. § P<0.005 MAP 20 min after infusion vs B. B, CoBF values. * P<0.05 CoBF 20 min after infusion vs B. # P<0.01 CoBF 20 min after infusion vs B. § P<0.05 CoBF of propofol dose 3, 20 min after infusion vs CoBF of propofol dose 2, 20 min after infusion. C, DPOAE amplitudes. * P<0.05 DPOAE amplitude 2 h after infusion vs B. # P<0.05 DPOAE amplitude 2 h after infusion of propofol dose 2 vs DPOAE amplitude 2 h after infusion of propofol dose 1.