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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: Addiction. 2014 Mar 17;109(6):965–976. doi: 10.1111/add.12512

Table 4.

Logistic regression analysis of genetic influence and gene x environment interaction on MIP compared to non-MIP

Univariate analyses
Wald df P values Adjusted ORs 95% CI
G x E interactionb (P values)
χ2, df P values Lower Upper
DBH gene a 4.9, 1 0.03 4 1 0.04 * 0.7 0.5 0.98 -
Severity of MA dependence 42, 1 <0.001 22 1 <0.001** 3.4 2.1 5.7 0.02 *
Antisocial personality 22, 1 <0.001 14 1 <0.001** 2.2 1.5 3.4 0.45
Alcohol dependence 21, 1 <0.001 4 1 0.05 1.4 1.0 2.1 0.99
Nicotine dependence 19, 1 <0.001 4 1 0.06 1.4 1.0 2.1 0.51

MIP = methamphetamine-induced paranoia, MA = methamphetamine, DBH = dopamine β-hydroxylase 95% CI = 95% confidence interval, df = degree of freedom, G x E = gene by environment

a

TT/CT compared to CC genotype.

b

After controlling for other clinical variables in the Table.

*

p < 0.05

**

p < 0.001